Berberine is a bioactive compound found in several plants, including the roots, rhizomes, and bark of various herbs from the Berberis genus, such as Berberis vulgaris (barberry), Berberis aristata (tree turmeric), and Coptis chinensis (Chinese goldthread). It has been used in traditional medicine systems, particularly in Chinese and Ayurvedic medicine, for centuries due to its health benefits. In this blog, we discuss some of the benefits and a brief history of berberine's use in medicine.